Chondroitin sulphate is found in nature in the cartilages that cushion the articulations, enabling them to carry out fluid movements.

A healthy cartilage consists in 65%-80% water, combined with collagen, chondrocytes and proteoglycans. When the natural balance of the components of the cartilage is upset, the cartilage becomes thinner and uneven. The results are an increase in the attrition between the bones (with the consequent onset of pain) and stiffening of the articulations that causes a decreased capacity of movement.

The action of Chondroitin sulphate, maintains the cartilages in a good state, attracting water to them, and supplying them with essential and lubricant nutriments. Chondroitin sulphate also inhibits cartilage degeneration caused by the enzymes, and stimulates the endogenous production of chondrocytes and proteoglycans.

Glucosamine is an amino saccharide that is produced naturally by the organism and it is necessary for the formation of tissues and fluids such as cartilages, tendons and ligaments, synovial fluid, mucous membranes and some structures of the eye, blood vessels and cardiac valves.

Glucosamine is one of the most common components to be found in animal tissues. When administered orally, as a dietary supplement, glucosamine is completely ionized in the stomach, it is absorbed in the gastro-intestinal tract and it binds actively to the articular tissues (as for example the cartilages).

Primary researches in the human field and in the veterinary field, have shown that glucosamine, taken as an oral dietary supplement, may have positive effects in the treatment of osteoarthritis.

Not positive in antidoping tests.